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Scientific Research & Evidence




REFERENCES:

”Testosterone and the Heart”
- Travis Goodale, M.D., Archana Sadhu, M.D., Steven Petak, M.D., J.D., and Richard Robbins, M.D.
Methodist Debakey Cardiovascular Journal. 2017 Apr-Jun; 13(2): 68–72.. doi: 10.14797/mdcj-13-2-68. PMCID: PMC5512682. PMID: 28740585
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5512682/

”A concise review of testosterone and bone health”
- Nur-Vaizura Mohamad, Ima-Nirwana Soelaiman, and Kok-Yong Chin
Clinical Interventations in Aging. 2016; 11: 1317–1324. Published online 2016 Sep 22. doi: 10.2147/CIA.S115472. PMCID: PMC5036835. PMID: 27703340
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036835/

”Circulating Testosterone as the Hormonal Basis of Sex Differences in Athletic Performance”
- David J Handelsman, Angelica L Hirschberg, and Stephane Bermon
Endocrine Society Reviews. 2018 Oct; 39(5): 803–829. Published online 2018 Jul 13. doi: 10.1210/er.2018-00020. PMCID: PMC6391653. PMID: 30010735
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391653/

”Randomized controlled trials – mechanistic studies of testosterone and the cardiovascular system”
- Asian Journal of Andrology. 2018 Mar-Apr; 20(2): 120–130. Published online 2018 Feb 9. doi: 10.4103/aja.aja_6_18. PMCID: PMC5858094. PMID: 29442075
T Hugh Jones and Daniel M Kelly
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858094/

”Testosterone Treatment and Sexual Function in Older Men With Low Testosterone Levels”
- Glenn R Cunningham, Alisa J Stephens-Shields, Raymond C Rosen, Christina Wang, Shalender Bhasin, Alvin M Matsumoto, J Kellogg Parsons, Thomas M Gill, Mark E Molitch, John T Farrar, David Cella, Elizabeth Barrett-Connor, Jane A Cauley, Denise Cifelli, Jill P Crandall, Kristine E Ensrud, Laura Gallagher, Bret Zeldow, Cora E Lewis, Marco Pahor, Ronald S Swerdloff, Xiaoling Hou, Stephen Anton, Shehzad Basaria, Susan J Diem, Vafa Tabatabaie, Susan S Ellenberg, Peter J Snyder 1
Randomized Controlled Trial - The Journal of Clinical Endocrinology and Metabolism . 2016 Aug;101(8):3096-104. doi: 10.1210/jc.2016-1645. Epub 2016 Jun 29.
https://pubmed.ncbi.nlm.nih.gov/27355400/

”Risks of testosterone replacement therapy in men”
- E. Charles Osterberg, Aaron M. Bernie, and Ranjith Ramasamy
Indian Journal of Urology. 2014 Jan-Mar; 30(1): 2–7. doi: 10.4103/0970-1591.124197. PMCID: PMC3897047. PMID: 24497673
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897047/

”Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo - controlled study”
- Elham Akhtari, Firoozeh Raisi, Mansoor Keshavarz, Hamed Hosseini, Farnaz Sohrabvand, Soodabeh Bioos, Mohammad Kamalinejad, Ali Ghobadi
Randomized Controlled Trial > Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences . 2014 Apr 28;22(1):40. doi: 10.1186/2008-2231-22-40. PMID: 24773615. PMCID: PMC4045980
https://pubmed.ncbi.nlm.nih.gov/24773615/

”Evaluation of the efficacy and safety of Tribulus terrestris in male sexual dysfunction-A prospective, randomized, double-blind, placebo-controlled clinical trial”
- Zdravko Kamenov, Svetlana Fileva, Krassimir Kalinov, Emmanuele A Jannini
Clinical Trial -> Maturitas . 2017 May;99:20-26. doi: 10.1016/j.maturitas.2017.01.011. Epub 2017 Feb 12. PMID: 28364864
https://pubmed.ncbi.nlm.nih.gov/28364864/

”Tribulus terrestris Extract Improves Human Sperm Parameters In Vitro”
- Sara Khaleghi, MSc, Mitra Bakhtiari, PhD Atefeh Asadmobini, MSc, and Farzane Esmaeili, BSc
Journal of Evidence-Based Complementary & Alternative Medicine. 2017 Jul; 22(3): 407–412. Published online 2016 Sep 30. doi: 10.1177/2156587216668110 PMCID: PMC5871152 PMID: 27694560
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5871152/

”Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action”
- Renuka Mani, Vijayakumar Natesan
Review -> Phytochemistry . 2018 Jan;145:187-196. doi: 10.1016/j.phytochem.2017.09.016. Epub 2017 Nov 20. PMID: 29161583
https://pubmed.ncbi.nlm.nih.gov/29161583/

”Erectogenic and Neurotrophic Effects of Icariin, a Purified Extract of Horny Goat Weed (Epimedium spp.) In Vitro and In Vivo”
- Alan W. Shindel, MD,* Zhong-Chen Xin, MD,† Guiting Lin, MD, PhD,* Thomas M. Fandel, MD,* Yun-Ching Huang, MD,* Lia Banie, BS,* Benjamin N. Breyer, MD,* Maurice M. Garcia, MD,* Ching-Shwun Lin, PhD,* and Tom F. Lue, MD*
Journal of Sex Med. Author manuscript; available in PMC 2013 Jan 22. Published in final edited form as: J Sex Med. 2010 Apr; 7(4 Pt 1): 1518–1528. Published online 2010 Feb 5. doi: 10.1111/j.1743-6109.2009.01699.x . PMCID: PMC3551978. NIHMSID: NIHMS431902, PMID: 20141584
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3551978/

”Eurycoma longifolia Jack in managing idiopathic male infertility”
- Mohd Ismail Bin Mohd Tambi, and M. Kamarul Imran
Asian Journal of Andrology. 2010 May; 12(3): 376–380. Published online 2010 Mar 29. doi: 10.1038/aja.2010.7. PMCID: PMC3739276. PMID: 20348942
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739276/

””
- Priyanga Ranasinghe, Shehani Pigera, Priyadarshani Galappatthy, Prasad Katulanda, and Godwin R. Constantine
DARU Journal of Pharmaceutical Sciences. 2015; 23(1): 44. Published online 2015 Sep 17. doi: 10.1186/s40199-015-0127-4
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214558/

”Review Ergogenic Effect of Long Jack, Eurycoma Longifolia”
- Thasanee Khanijo and Wannee Jiraungkoorskul
Pharmacognosy Review. 2016 Jul-Dec; 10(20): 139–142. doi: 10.4103/0973-7847.194041. PMCID: PMC5214558. PMID: 28082797
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5214558/

”In Vitro. and In Vivo. Evaluation of Free-Radical Scavenging Potential of Cissus quadrangularis.”
- Mallika Jainu &C.S. Shyamala Devi
Pharmaceutical Biology Volume 43, 2005 - Issue 9. https://doi.org/10.1080/13880200500406636
https://www.tandfonline.com/doi/full/10.1080/13880200500406636

”Effects of human growth hormone in men over 60 years old”
- D Rudman, A G Feller, H S Nagraj, G A Gergans, P Y Lalitha, A F Goldberg, R A Schlenker, L Cohn, I W Rudman, D E Mattson
The New England Journal of Medicine. 1990 Jul 5;323(1):1-6. doi: 10.1056/NEJM199007053230101. PMID: 2355952 DOI: 10.1056/NEJM199007053230101
https://pubmed.ncbi.nlm.nih.gov/2355952/

”The exercise-induced growth hormone response in athletes”
- Richard J Godfrey 1, Zahra Madgwick, Gregory P Whyte
Sports Medicine (Auckland, NZ). 2003;33(8):599-613. doi: 10.2165/00007256-200333080-00005.
https://pubmed.ncbi.nlm.nih.gov/12797841/